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How To Choose A Good Waste Management Company For Your Organization

Waste management services may look simple on the surface, but the reality is, it is quite tricky. When searching for waste management in Austin, you have to balance your budget and needs for the services that are to be provided. Here are some tips so that you choose the right service for your organization.Check at PricesThe fact is your company has to make money and you want to become successful. Choosing services no matter how important that is not within your budget will provide hindrance on your path to success. This is the reason pricing is an important consideration for waste management in Austin. Before going for the right service provider, always figure out a budget and make sure to balance your needs with the available funds. You will probably find what you require at a price you love. If a service is terrible or not covering your requirements, then it is a waste of money and you have to search soon for a trusted company.Check the ServicesDoes your restaurant require grease services regularly? Do you have a lot of restricted or toxic waste that has to go through proper channels? Are you into a landscape business that requires a daily visit to the compost areas? When opting for services in Austin, it is vital that you consider exactly what you require. There are different kinds of waste management services are there in the market, so it is crucial that you pick the right one for your business. Nowadays everything is digital and all good waste management companies have enlisted their services online. Go through the services and for any clarification, dial the help desk number.ExperienceWaste management in Austin is much more than driving garbage around. It is all about disposing of safely and complying with the regulations of your waste products. Doing it in the right way involves understanding the safety of waste disposal, especially when doing in an efficient way, but also doing by strictly adhering to laws and regulations. This is the main reason you need to find a firm that has years of experience. Choose a company that knows what they are actually doing, especially when it is about professional waste management services.FutureIn Austin, most services for waste management are based on daily pickups with an agreement done on waste limits. When choosing the best plans, you will stay under budget while getting the desired services. However, some plans can be quite restrictive. Rather than picking a plan that has a fixed amount, make sure whatever agreement you do must have room for growth and can be adaptable as your business succeeds and changes. Check all the instructions, terms and conditions and consult with your provider so that you can easily change without any major inconveniences or penalties. There are several reputed waste management firms in Austin where you can book an appointment for a consultation and they will be happy to provide you free quotation.

[youtube]http://www.youtube.com/watch?v=Ervb3qX_xi8[/youtube]

Sprint Nextel customer service rep. harasses client; Sprint cancels his account

Sunday, July 22, 2007

Virginia – Joshua Brady, a former Sprint Nextel customer, has had his cellular phone account shut off, but not because he wasn’t paying the phone bill, or even because he was late on payments, but because a customer service representative who assisted him, began to call him outside of her job, and make death threats to him in September of 2006. She was never fired for her actions, Brady says.

Brady has agreed to be interviewed by Wikinews to tell his story. All information and claims have been logged with Brady’s attorney and federal authorities.

The representative from Sprint Nextel, who for safety reasons is only being identified as Jessica, was working at the company’s call center in Ontario, Canada where Brady’s call to customer service was directed. According to Brady, Jessica then began to call him outside of her job duties at the call center after their first contact.

Brady called the center around 6:00 p.m. (eastern time) on a Saturday and attempted to receive help on a billing question and to find a way to stop prank calls. Brady requested a “soc code”, a code placed into the phone, that would allow for the number that was pranking him to be blocked. Unfortunately, Jessica did not know what that was, but tried unsuccessfully to find it. According to Brady, the only thing she could find was “the ANI feature call centers have.”

Brady then described to Jessica the billing issue he was having. He was being charged “for text messages I was not making”, even though he had unlimited text messaging with his billing plan. Meanwhile, Jessica called for a supervisor to help locate the code. As this customer service request over the phone was taking quite a bit of time, the two of them then started to discuss what two people would normally discuss if just chatting; sports, the weather, movies and music and if Virginia was a nice place to go on vacation. The supervisor then came by Jessica’s station with no luck on finding a code.

Later that night, around 10:30 p.m., Brady received a call. He answered it and much to his surprise, it was Jessica. He answered the phone with the usual “hello” and the voice on the other end answered with “hello Josh.” Brady was “surprised” that she had not said “hello Mr. Brady.”

“I then asked who it was, and she said Jessica. She told me about her day, and hoped that I did not mind her calling.” Then according to Brady, she started to describe how much she hated working in a call center, and how the job “pays the bills”, and asked if she could “come visit me sometime”. Brady said that he “immediately started to record” the call. Brady also stated that Jessica was not aware she was being recorded, and that further conversations were recorded without her knowing.

The call lasted about 15 minutes, but Brady said she “spoke so fast and moved along through things” that he “didn’t have a chance to talk if I wanted to. It [the call] ended with me interrupting her and telling her I had to go to dinner with a friend.”

Brady immediately called customer care back and reported Jessica’s actions to a supervisor (Jason), and the Floor Manager (Also named Jessica) at the Coos Bay call center, which is where his call happened to be directed. The advice he received was to “play along” and continue to report her actions until they could locate someone “better equipped” to handle the situation.

Jessica then began to call “about every other day or so” which turned out to be almost 30 calls, according to Brady who reported each call she made to Sprint Nextel.

Sprint Nextel then told Jessica to cease and desist all contact with Brady, but that didn’t stop Jessica from contacting him. She somehow found out the screen-name of his AOL Instant Messenger account, and left messages threatening to kill him. Brady logged the messages and faxed them to Sprint, who about a week later sent Brady a letter, saying that his accounts have been terminated.

“The purpose of this letter is to inform our that our office has received a complaint regarding your recent questionable interactions with our customer care group. Recent interactions with our company have prompted us to formally contact you. Sprint Nextel terms and conditions state that “termination of services. consistent with this agreement…”, said the letter from Sprint Nextel.

Brady states that Jessica is still employed with Sprint Nextel, despite the fact that all instant messages left by Jessica were forwarded to Sprint Nextel.

As recently as July 10, 2007, as many as 1,000 accounts were terminated by Sprint Nextel because customers were complaining too much and asking too many questions about billing.

“While we have worked to resolve your issues and questions to the best of our ability, the number of inquiries you have made to us during this time had led us to determine that we are unable to meet your current wireless needs,” said one letter to a sprint customer as recent as June 29, 2007. The letter states that the service will be terminated just one day after the letter was written despite saying they “understand switching to a new carrier causes an inconvenience.”

Two weeks ago, Sprint addressed the media about the mass-cancellations. “These accounts have been researched very carefully,” Sprint spokeswoman Roni Singleton said. “We feel strongly that the decisions we made, we stand by them. These decisions weren’t made lightly.”

“If the average person is calling less than once per month and these people are calling 40 or 50 times more, that takes away from customer service,” Singleton said. “Our priority is to improve the customer experience.”

Wikinews sent e-mails to Sprint Nextel on July 20 regarding the Brady incident; to date no response has been received.

Update: On July 23, 2007, Wikinews received an email response from a Sprint representative, going to some length to explain the termination of the customers who were calling up to hundreds of times a month. No information was given on the Brady case covered in this article; “customer privacy considerations” were cited as the reason and “no comment” was Sprint’s reply.

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India discontinues ?500, ?1000 denominations; releases ?2000 and new ?500 bills

Monday, November 14, 2016

On Wednesday, India demonetised ?500 (about US$7.50) and ?1000 notes, announced as a measure to fight corruption, fake notes, and black money. Prime Minister Narendra Modi addressed the Indian citizens late Tuesday, and said 500 and 1000 rupee notes would cease to be legal tender at midnight.

To minimise possible difficulties to citizens, transactions using old 500 and 1000 rupee notes were accepted at government hospitals, railway ticket bookings, government buses, and airports. The notes were also accepted at public-sector petrol-pumps, government-authorised consumer co-operative stores, milk booths authorised by State governments, and cremation grounds till Friday midnight. These shops were obliged to have a record of their stocks and sales.

In his announcement, Modi said, “For your immediate needs, you can go to any bank, head post office or sub post office, show your identity proof like Aadhar card, voter’s card, ration card, passport, income tax PAN card number or other approved proofs and exchange your old 500 or thousand rupee notes for new notes.” ((hi))Hindi language: ??????? ???????? ?? ??? ???? ?? ?? ?? ???? ?? ?????? ????? ?? ??? ??? ?????? ????? ?? ??? ?? ????? ?? ??? ?????? ?? ?? ???? ?? ???? ?? ?????? ?? ?? ??? ?? ?? ?????? ?? ???? ????? ????, ???? ??, ???? ?????, ?????? ?????, ???? ?????, ????????, ???? ????? ??? ????? ??????? ???? ?? ??? ??? ??? ???? ?? ??? ??? ???? ???

Modi also announced those who failed to change their currency till December 30 can exchange the notes at Reserve Bank of India (RBI)’s office along with a declaration form till March 31. The notes can be exchanged till December 30 at any branch of any bank across India.

By Saturday, Finance Minister Arun Jaitley said demonetised money equivalent to almost US$30 billion was deposited in banks across India. According to estimate, the old notes accounted for 85% of the total money in circulation. New 500 rupee and 2000 rupee notes are to be issued. Modi said RBI would exercise caution from past experience and limit the circulation of large-value notes.

International tourists could purchase up to 5000 rupees using the old notes at airport exchanges till Friday.

A limit was imposed on cash withdrawal; a maximum of 10000 rupees each day, and 20000 rupees each week, can be withdrawn. Moreover, from Thursday (November 10) till November 24, 4000 rupees can be exchanged in the banks and post offices. The amount is credited to the bank account.

Government workers were informed about demonetising when the announcement was made. Modi announced all banks would remain closed for public work on Wednesday.

In the United States, Donald Trump won the 2016 presidential election on Tuesday, immediately after which stock markets dropped globally. Following the US election and demonetising the money, the Indian stock market fell by 1700 points on Wednesday. Sensex lost 1,688.69 points and Nifty lost 111.55 points on the same day. Indian technology sector companies experienced loss. TCS suffered 4.93% loss and Infosys lost 2.74%.

The Indian rupee is also used in the neighbouring countries of Bhutan and Nepal. The border area uses Indian currency for day-to-day transactions. The Royal Monetary Authority of Bhutan (RMA) has announced the exchange of old notes will be facilitated till December 15. RMA governor Dasho Penjore informed Indian news site The Wire, “We do not know exactly how much Indian currency of Rs 500 and Rs 1,000 is in circulation in Bhutan. We will get a better idea after the deadline to deposit their amount”. RMA has 30% of its international exchange reserve in Indian rupees. Nepal Rastra Bank directed all Nepali banks to stop conducting transactions using the Indian rupee.

On Thursday, there were long queues in front of ATMs and banks to exchange the old notes and withdraw money. BBC reported some banks ran out of cash. Police were called to some banks to maintain discipline. Banks were open on Saturday and Sunday for money exchange.

Shops did not accept the old 500 and 1000 rupee notes. Some emphasised cash-less transaction as well. BBC reported some traders and small business owners in Delhi threatened to call a strike as this move affected their business.

eRetail websites like Amazon and Flipkart announced they would not accept the old 500 and 1000 rupee notes on Cash on Delivery orders. Amazon also announced 15% discount on gift cards worth 500 or 1000 rupees.

The government ceased all transactions using the old 500 and 1000 rupee notes before Saturday. But a Wikinews correspondent noticed a jeweler shop accepting the demonetised notes on Saturday. When questioned, the jeweler said they were accepting the old notes only on purchase. When the correspondent, who did not identify as a reporter to the shop owners, said the old 500 and 1000 rupee notes were not legal money, they said they will exchange the notes in a bank since there were 50 days to exchange with a new and legal tender. They refused to exchange old 500 rupee notes with change, asserting the customer needs to buy merchandise from their shop.

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Ingrid Newkirk, co-founder of PETA, on animal rights and the film about her life

Tuesday, November 20, 2007

Last night HBO premiered I Am An Animal: The Story of Ingrid Newkirk and PETA. Since its inception, People for the Ethical Treatment of Animals (PETA) has made headlines and raised eyebrows. They are almost single-handedly responsible for the movement against animal testing and their efforts have raised the suffering animals experience in a broad spectrum of consumer goods production and food processing into a cause célèbre.

PETA first made headlines in the Silver Spring monkeys case, when Alex Pacheco, then a student at George Washington University, volunteered at a lab run by Edward Taub, who was testing neuroplasticity on live monkeys. Taub had cut sensory ganglia that supplied nerves to the monkeys’ fingers, hands, arms, legs; with some of the monkeys, he had severed the entire spinal column. He then tried to force the monkeys to use their limbs by exposing them to persistent electric shock, prolonged physical restraint of an intact arm or leg, and by withholding food. With footage obtained by Pacheco, Taub was convicted of six counts of animal cruelty—largely as a result of the monkeys’ reported living conditions—making them “the most famous lab animals in history,” according to psychiatrist Norman Doidge. Taub’s conviction was later overturned on appeal and the monkeys were eventually euthanized.

PETA was born.

In the subsequent decades they ran the Stop Huntingdon Animal Cruelty against Europe’s largest animal-testing facility (footage showed staff punching beagle puppies in the face, shouting at them, and simulating sex acts while taking blood samples); against Covance, the United State’s largest importer of primates for laboratory research (evidence was found that they were dissecting monkeys at its Vienna, Virginia laboratory while the animals were still alive); against General Motors for using live animals in crash tests; against L’Oreal for testing cosmetics on animals; against the use of fur for fashion and fur farms; against Smithfield Foods for torturing Butterball turkeys; and against fast food chains, most recently against KFC through the launch of their website kentuckyfriedcruelty.com.

They have launched campaigns and engaged in stunts that are designed for media attention. In 1996, PETA activists famously threw a dead raccoon onto the table of Anna Wintour, the fur supporting editor-in-chief of Vogue, while she was dining at the Four Seasons in New York, and left bloody paw prints and the words “Fur Hag” on the steps of her home. They ran a campaign entitled Holocaust on your Plate that consisted of eight 60-square-foot panels, each juxtaposing images of the Holocaust with images of factory farming. Photographs of concentration camp inmates in wooden bunks were shown next to photographs of caged chickens, and piled bodies of Holocaust victims next to a pile of pig carcasses. In 2003 in Jerusalem, after a donkey was loaded with explosives and blown up in a terrorist attack, Newkirk sent a letter to then-PLO leader Yasser Arafat to keep animals out of the conflict. As the film shows, they also took over Jean-Paul Gaultier‘s Paris boutique and smeared blood on the windows to protest his use of fur in his clothing.

The group’s tactics have been criticized. Co-founder Pacheco, who is no longer with PETA, called them “stupid human tricks.” Some feminists criticize their campaigns featuring the Lettuce Ladies and “I’d Rather Go Naked Than Wear Fur” ads as objectifying women. Of their Holocaust on a Plate campaign, Anti-Defamation League Chairman Abraham Foxman said “The effort by PETA to compare the deliberate systematic murder of millions of Jews to the issue of animal rights is abhorrent.” (Newkirk later issued an apology for any hurt it caused). Perhaps most controversial amongst politicians, the public and even other animal rights organizations is PETA’s refusal to condemn the actions of the Animal Liberation Front, which in January 2005 was named as a terrorist threat by the United States Department of Homeland Security.

David Shankbone attended the pre-release screening of I Am An Animal at HBO’s offices in New York City on November 12, and the following day he sat down with Ingrid Newkirk to discuss her perspectives on PETA, animal rights, her responses to criticism lodged against her and to discuss her on-going life’s work to raise human awareness of animal suffering. Below is her interview.

This exclusive interview features first-hand journalism by a Wikinews reporter. See the collaboration page for more details.
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Finding A Family Dentist In Appleton

byAlma Abell

Very few people out there actually like going to the dentist. While they may put up with it, they don’t exactly love the idea of several aspects of going to the dentist. First off, they don’t like the idea of someone “tinkering” inside of their mouth for nearly an hour. Secondly, they hate the idea of them using that hooked “scrapper” thing to get plaque off of their teeth. Third, they are afraid of the idea that they are going to get bad news when they visit the dentist. They are afraid that they are going to be told that they need a cavity to get filled, or that they are having problems with their gums. Ironically, though, the more that you end up going to the dentist, the less you are going to have to deal with these types of problems.

[youtube]http://www.youtube.com/watch?v=p1yHpgwv8N4[/youtube]

Even though you may not love the idea of going to the dentist, you need to go at least once every six months to get your teeth looked at. It may not be the most pleasant thing for you to do, but the fact is that, well, it is the kind of thing that you need to do. Plus, going to the family dentist in Appleton is never as bad as you think it is going to be. Sure, it might be a bit annoying, but with the right dentist you are never going to be in that much discomfort, and the pain is going to be nearly non-existent. Plus, if you get the right dentist, you can have fun conversations when you are in the chair.

When you are looking for a Family Dentist in Appleton, you are going to have a lot of options to consider. If you have insurance you want to look for someone who takes your coverage. If you don’t have insurance, look for someone who is going to be able to give you a good cash price. All in all, you want to find someone that you are happy with, and that you feel like you can get along with. One option you want to consider is Dr.

Australian nuclear power plants rejected by states

Monday, June 5, 2006

Wikinews Australia has in-depth coverage of this issue: Australian nuclear debate

Australian media reports that Prime Minister John Howard is expected to push a nuclear energy inquiry through federal cabinet this week. Meanwhile, a list of possible sites for nuclear reactors has been leaked by the Opposition to media. The locations, listed in 1997, include Adelaide, Darwin, Perth, Lucas Heights, Goulburn, Holsworthy, and Broken Hill in New South Wales and other sites.

West Australian (WA) premier Alan Carpenter says the list of fourteen potential sites were a “facade to soften up Western Australians into accepting a nuclear waste dump.” The WA Premier said people would not only be surprised but “stunned to learn that the federal cabinet considered possible sites… without disclosing them to any state government.”

Mr Carpenter said in a media release that the document mentions a site near Perth airport. “People should wake up to what’s happening around Australia, particularly in WA,” said Mr. Carpenter. “Only a few weeks ago, we had three prominent WA Liberal MPs supporting a nuclear waste dump in WA,” he said. “This is all a facade in the Howard Government’s push to soften up West Australians for a nuclear waste dump.”

Premier Carpenter, whose Labor government stridently opposes uranium mining in WA, stated his opposition to a nuclear waste dump: “I vehemently oppose the prospect of our State becoming the dumping ground for the world’s nuclear waste and that is what will happen if we allow uranium mining in WA. The evidence is mounting and indisputable.”

The South Australian Government has ruled out any possible nuclear power plant in SA. “A nuclear power plant would bankrupt our state,” SA Premier Mike Rann said. “It would not be commercially viable and would not, in my view, be acceptable to the public. Nuclear power plants need giant populations to sustain them, there is no-one coming to me from the commercial sector or the mining industry or anywhere else, suggesting a nuclear power plant.”

Earlier, Foreign Affairs Minister Alexander Downer said South Australia should build a nuclear power station to run a desalination plant. Premier Rann dismissed the idea as ridiculous and said comments by Mr Downer highlight divisions within Federal Cabinet. He said Mr Downer is at odds with the Federal Finance Minister Nick Minchin, who says the high costs of nuclear power would rule it out.

Mr Rann says South Australia will not allow nuclear power. “For once I’m agreeing with Nick Minchin,” he said. “I think Nick Minchin is right that a nuclear power plant isn’t necessary and won’t happen and I think that Alexander Downer is having a bit of a lend of him.”

Victoria’s Energy Minister Theo Theophanous said nuclear energy in Australia did not make sense when the cost and problems of waste disposal were considered. Mr Theophanous has rejected a report that found nuclear power could be competitive with conventional energy generation if it was subsided with help from a taxpayer subsidy.

A recent report found nuclear power could compete with gas or coal-fired electricity if taxpayers helped to pay for it or shouldered the risk of its production. The ANSTO report found nuclear plants could be built in the next 10 to 15 years and an Australian version would cost about $2.5 billion to establish. To make it viable, taxpayers would pay hundreds of million towards start-up costs, said the report.

But Mr Theophanous said Victoria had already had concluded the nuclear proposal did not add up. “I had my department look at this and provide a report to me more than a year ago in relation to the prospect of nuclear power,” he said. “The problem is a commercial one as much as anything else. It costs roughly double the price to produce power out of nuclear energy. If you’re going to pay double the price, why not put in wind farms? Why not use renewable energy, which is even cheaper than nuclear energy?” said Mr Theophanous .

The Victoria Government urges householders to reduce greenhouse emissions by reducing daily energy consumption. A new campaign identifies simple measures residents can adopt to cut power bills and greenhouse emissions, including turning the heating thermostat to no more than 20C, washing clothes in cold water and turning appliances off at the switch when they are not being used.

New South Wales Premier Morris Iemma has also declared his opposition to nuclear power. He said no nuclear power stations would be built in NSW as long as he is premier. Mr Iemma urged state opposition leader Peter Debnam to join him in opposing the construction of nuclear power plants in NSW. “While ever I’m premier of NSW there won’t be any nuclear power plants in NSW,” he told reporters.

Queensland Premier Peter Beattie says he “would not jeopardize the state’s coal industry by supporting a nuclear power plant.” Mr. Beattie has ruled out uranium mining in Queensland to protect the state’s huge coal industry. He said he would not support a nuclear power plant. “The State Government would not support it,” Mr. Beattie said.

“We have the power to block them and we would block them, we would not support nuclear power. Why would we have a nuclear reactor in competition with the coal industry?” Mr. Beattie told media.

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President Obama renews his push to close Guantanamo detention facility

Friday, May 3, 2013

With over 100 Guantanamo Bay detainees in a hunger strike against their incarceration, President Barack Obama, on Tuesday, renewed his push for the closure of the facility.

President Obama addressed a news conference at the White House on Tuesday saying he would have a team of officials review the issue before again appealing to Congress to close the prison holding “terror” suspects in Cuba. “I think it is critical for us to understand that Guantanamo is not necessary to keep America safe,” he said. “It is expensive. It is inefficient. It hurts us in terms of our international standing. It lessens co-operation with our allies on counter-terrorism efforts. It is a recruitment tool for extremists. It needs to be closed.”

These remarks were made after 40 US Navy medical staff were sent to the facility to deal with the growing hunger strike that began on February 6 this year, where twenty one inmates are now being force fed; five of those are in hospital. “I don’t want these individuals to die,” President Obama said.

Calls by the Center for Constitutional Rights however, have called for President Obama to transfer men from the facility now; a power he has over Congress. “He should use the certification/waiver process created by Congress to transfer detainees, starting with the 86 men who have been cleared for release,” the New York-based group said.

When asked for greater details about President Obama’s intentions, National Security Council spokeswoman Caitlin Hayden said the president was “considering a range of options for ways that we can reduce the population there,” including “reappointing a senior official at the State Department to renew our focus on repatriating or transferring” lower-risk detainees.

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Buy Pre Owned Bmw Model And Drive Your Dream}

Buy Pre-Owned BMW Model and Drive your Dream

by

AdityaA desire to own a luxury car like BMW has made car enthusiasts to visit dealerships like BMW Motors. But this time, not to invest in a brand new model but a pre-owned one. The upper-middle class in major cities of India like Ahmedabad, Surat and Rajkot is increasingly headed for the much affordable automobile segment pre-owned luxury cars. If market reports have to be believed, the demand for second-hand BMW cars has increased up to 30% in the last few years and all credit goes to their price, which is just the half of a new one.

For an average middle class, it is not easy to buy a car you have been eyeing on for so long. But, there are BMW certified dealers like BMW Motors who sells used models of lavish car brands. This gives you an opportunity to buy luxury automobiles at an affordable price.

How the idea of selling certified pre-owned luxury vehicles came into the picture?

A typical premium car-owner changes his car after every 1 or 2 years and, therefore, a good number of second-hand BMW cars are now available in the automobile market. Then there was a new set of emerging buyers who wish to own a lavish BMW model, but don’t want to spend too much. As a result, lavish car marques like BMW started a new concept of certified pre-owned (CPO) vehicles. The leasing option rolled by this automaker has further added second-hand vehicles into their inventory.

The trend of buying certified used models is not only visible in small towns but also big cities like Ahmedabad, Surat, and Rajkot. The newly rich who want to be a part of the elite club consider buying used vehicles that cost much less. The lower cost and less depreciation of used vehicles further make the used luxury car purchase an attractive proposition.

What are the benefits of owning a certified second-hand BMW car?

Buying a certified pre-owned model is pretty much safe and therefore considered a sensible decision.

1.Each and every used BMW model is put on sale only after going through multiple checkpoints and completely refurbished technically and visually. In case of an issue, the mechanical parts are replaced by genuine BMW spare parts. Further, the used car comes with the manufacturer-backed warranty of 2 years or up to 50,000 miles, whichever comes earlier.

2.Pre-owned models displayed at BMW Motors come with customized financing options. With BMW finance options, you can look forward to special loyalty benefits, quick approvals with fast turnaround times, part payment facilities. To ensure the best-in-class customer interaction, they have an in-house call centre as well.

3.When you are enjoying a luxurious drive, be ready to see heads turning around and jaw dropping. No one will ever know whether you have purchased a new one or driving a pre-owned model till the time they have the eye of differentiating the luxury vehicles.

Article Source:

eArticlesOnline.com}

Cleveland, Ohio clinic performs US’s first face transplant

Thursday, December 18, 2008

A team of eight transplant surgeons in Cleveland Clinic in Ohio, USA, led by reconstructive surgeon Dr. Maria Siemionow, age 58, have successfully performed the first almost total face transplant in the US, and the fourth globally, on a woman so horribly disfigured due to trauma, that cost her an eye. Two weeks ago Dr. Siemionow, in a 23-hour marathon surgery, replaced 80 percent of her face, by transplanting or grafting bone, nerve, blood vessels, muscles and skin harvested from a female donor’s cadaver.

The Clinic surgeons, in Wednesday’s news conference, described the details of the transplant but upon request, the team did not publish her name, age and cause of injury nor the donor’s identity. The patient’s family desired the reason for her transplant to remain confidential. The Los Angeles Times reported that the patient “had no upper jaw, nose, cheeks or lower eyelids and was unable to eat, talk, smile, smell or breathe on her own.” The clinic’s dermatology and plastic surgery chair, Francis Papay, described the nine hours phase of the procedure: “We transferred the skin, all the facial muscles in the upper face and mid-face, the upper lip, all of the nose, most of the sinuses around the nose, the upper jaw including the teeth, the facial nerve.” Thereafter, another team spent three hours sewing the woman’s blood vessels to that of the donor’s face to restore blood circulation, making the graft a success.

The New York Times reported that “three partial face transplants have been performed since 2005, two in France and one in China, all using facial tissue from a dead donor with permission from their families.” “Only the forehead, upper eyelids, lower lip, lower teeth and jaw are hers, the rest of her face comes from a cadaver; she could not eat on her own or breathe without a hole in her windpipe. About 77 square inches of tissue were transplanted from the donor,” it further described the details of the medical marvel. The patient, however, must take lifetime immunosuppressive drugs, also called antirejection drugs, which do not guarantee success. The transplant team said that in case of failure, it would replace the part with a skin graft taken from her own body.

Dr. Bohdan Pomahac, a Brigham and Women’s Hospital surgeon praised the recent medical development. “There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Leading bioethicist Arthur Caplan of the University of Pennsylvania withheld judgment on the Cleveland transplant amid grave concerns on the post-operation results. “The biggest ethical problem is dealing with failure — if your face rejects. It would be a living hell. If your face is falling off and you can’t eat and you can’t breathe and you’re suffering in a terrible manner that can’t be reversed, you need to put on the table assistance in dying. There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Dr Alex Clarke, of the Royal Free Hospital had praised the Clinic for its contribution to medicine. “It is a real step forward for people who have severe disfigurement and this operation has been done by a team who have really prepared and worked towards this for a number of years. These transplants have proven that the technical difficulties can be overcome and psychologically the patients are doing well. They have all have reacted positively and have begun to do things they were not able to before. All the things people thought were barriers to this kind of operations have been overcome,” she said.

The first partial face transplant surgery on a living human was performed on Isabelle Dinoire on November 27 2005, when she was 38, by Professor Bernard Devauchelle, assisted by Professor Jean-Michel Dubernard in Amiens, France. Her Labrador dog mauled her in May 2005. A triangle of face tissue including the nose and mouth was taken from a brain-dead female donor and grafted onto the patient. Scientists elsewhere have performed scalp and ear transplants. However, the claim is the first for a mouth and nose transplant. Experts say the mouth and nose are the most difficult parts of the face to transplant.

In 2004, the same Cleveland Clinic, became the first institution to approve this surgery and test it on cadavers. In October 2006, surgeon Peter Butler at London‘s Royal Free Hospital in the UK was given permission by the NHS ethics board to carry out a full face transplant. His team will select four adult patients (children cannot be selected due to concerns over consent), with operations being carried out at six month intervals. In March 2008, the treatment of 30-year-old neurofibromatosis victim Pascal Coler of France ended after having received what his doctors call the worlds first successful full face transplant.

Ethical concerns, psychological impact, problems relating to immunosuppression and consequences of technical failure have prevented teams from performing face transplant operations in the past, even though it has been technically possible to carry out such procedures for years.

Mr Iain Hutchison, of Barts and the London Hospital, warned of several problems with face transplants, such as blood vessels in the donated tissue clotting and immunosuppressants failing or increasing the patient’s risk of cancer. He also pointed out ethical issues with the fact that the procedure requires a “beating heart donor”. The transplant is carried out while the donor is brain dead, but still alive by use of a ventilator.

According to Stephen Wigmore, chair of British Transplantation Society’s ethics committee, it is unknown to what extent facial expressions will function in the long term. He said that it is not certain whether a patient could be left worse off in the case of a face transplant failing.

Mr Michael Earley, a member of the Royal College of Surgeon‘s facial transplantation working party, commented that if successful, the transplant would be “a major breakthrough in facial reconstruction” and “a major step forward for the facially disfigured.”

In Wednesday’s conference, Siemionow said “we know that there are so many patients there in their homes where they are hiding from society because they are afraid to walk to the grocery stores, they are afraid to go the the street.” “Our patient was called names and was humiliated. We very much hope that for this very special group of patients there is a hope that someday they will be able to go comfortably from their houses and enjoy the things we take for granted,” she added.

In response to the medical breakthrough, a British medical group led by Royal Free Hospital’s lead surgeon Dr Peter Butler, said they will finish the world’s first full face transplant within a year. “We hope to make an announcement about a full-face operation in the next 12 months. This latest operation shows how facial transplantation can help a particular group of the most severely facially injured people. These are people who would otherwise live a terrible twilight life, shut away from public gaze,” he said.

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Cleveland, Ohio clinic performs US’s first face transplant

Thursday, December 18, 2008

A team of eight transplant surgeons in Cleveland Clinic in Ohio, USA, led by reconstructive surgeon Dr. Maria Siemionow, age 58, have successfully performed the first almost total face transplant in the US, and the fourth globally, on a woman so horribly disfigured due to trauma, that cost her an eye. Two weeks ago Dr. Siemionow, in a 23-hour marathon surgery, replaced 80 percent of her face, by transplanting or grafting bone, nerve, blood vessels, muscles and skin harvested from a female donor’s cadaver.

The Clinic surgeons, in Wednesday’s news conference, described the details of the transplant but upon request, the team did not publish her name, age and cause of injury nor the donor’s identity. The patient’s family desired the reason for her transplant to remain confidential. The Los Angeles Times reported that the patient “had no upper jaw, nose, cheeks or lower eyelids and was unable to eat, talk, smile, smell or breathe on her own.” The clinic’s dermatology and plastic surgery chair, Francis Papay, described the nine hours phase of the procedure: “We transferred the skin, all the facial muscles in the upper face and mid-face, the upper lip, all of the nose, most of the sinuses around the nose, the upper jaw including the teeth, the facial nerve.” Thereafter, another team spent three hours sewing the woman’s blood vessels to that of the donor’s face to restore blood circulation, making the graft a success.

The New York Times reported that “three partial face transplants have been performed since 2005, two in France and one in China, all using facial tissue from a dead donor with permission from their families.” “Only the forehead, upper eyelids, lower lip, lower teeth and jaw are hers, the rest of her face comes from a cadaver; she could not eat on her own or breathe without a hole in her windpipe. About 77 square inches of tissue were transplanted from the donor,” it further described the details of the medical marvel. The patient, however, must take lifetime immunosuppressive drugs, also called antirejection drugs, which do not guarantee success. The transplant team said that in case of failure, it would replace the part with a skin graft taken from her own body.

Dr. Bohdan Pomahac, a Brigham and Women’s Hospital surgeon praised the recent medical development. “There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Leading bioethicist Arthur Caplan of the University of Pennsylvania withheld judgment on the Cleveland transplant amid grave concerns on the post-operation results. “The biggest ethical problem is dealing with failure — if your face rejects. It would be a living hell. If your face is falling off and you can’t eat and you can’t breathe and you’re suffering in a terrible manner that can’t be reversed, you need to put on the table assistance in dying. There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Dr Alex Clarke, of the Royal Free Hospital had praised the Clinic for its contribution to medicine. “It is a real step forward for people who have severe disfigurement and this operation has been done by a team who have really prepared and worked towards this for a number of years. These transplants have proven that the technical difficulties can be overcome and psychologically the patients are doing well. They have all have reacted positively and have begun to do things they were not able to before. All the things people thought were barriers to this kind of operations have been overcome,” she said.

The first partial face transplant surgery on a living human was performed on Isabelle Dinoire on November 27 2005, when she was 38, by Professor Bernard Devauchelle, assisted by Professor Jean-Michel Dubernard in Amiens, France. Her Labrador dog mauled her in May 2005. A triangle of face tissue including the nose and mouth was taken from a brain-dead female donor and grafted onto the patient. Scientists elsewhere have performed scalp and ear transplants. However, the claim is the first for a mouth and nose transplant. Experts say the mouth and nose are the most difficult parts of the face to transplant.

In 2004, the same Cleveland Clinic, became the first institution to approve this surgery and test it on cadavers. In October 2006, surgeon Peter Butler at London‘s Royal Free Hospital in the UK was given permission by the NHS ethics board to carry out a full face transplant. His team will select four adult patients (children cannot be selected due to concerns over consent), with operations being carried out at six month intervals. In March 2008, the treatment of 30-year-old neurofibromatosis victim Pascal Coler of France ended after having received what his doctors call the worlds first successful full face transplant.

Ethical concerns, psychological impact, problems relating to immunosuppression and consequences of technical failure have prevented teams from performing face transplant operations in the past, even though it has been technically possible to carry out such procedures for years.

Mr Iain Hutchison, of Barts and the London Hospital, warned of several problems with face transplants, such as blood vessels in the donated tissue clotting and immunosuppressants failing or increasing the patient’s risk of cancer. He also pointed out ethical issues with the fact that the procedure requires a “beating heart donor”. The transplant is carried out while the donor is brain dead, but still alive by use of a ventilator.

According to Stephen Wigmore, chair of British Transplantation Society’s ethics committee, it is unknown to what extent facial expressions will function in the long term. He said that it is not certain whether a patient could be left worse off in the case of a face transplant failing.

Mr Michael Earley, a member of the Royal College of Surgeon‘s facial transplantation working party, commented that if successful, the transplant would be “a major breakthrough in facial reconstruction” and “a major step forward for the facially disfigured.”

In Wednesday’s conference, Siemionow said “we know that there are so many patients there in their homes where they are hiding from society because they are afraid to walk to the grocery stores, they are afraid to go the the street.” “Our patient was called names and was humiliated. We very much hope that for this very special group of patients there is a hope that someday they will be able to go comfortably from their houses and enjoy the things we take for granted,” she added.

In response to the medical breakthrough, a British medical group led by Royal Free Hospital’s lead surgeon Dr Peter Butler, said they will finish the world’s first full face transplant within a year. “We hope to make an announcement about a full-face operation in the next 12 months. This latest operation shows how facial transplantation can help a particular group of the most severely facially injured people. These are people who would otherwise live a terrible twilight life, shut away from public gaze,” he said.

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